Acetyl-L-carnitine is also known as ALC. It is used by some people with high blood sugar to help with cholesterol as well as nerve pain, such as tingling in their hands and feet. Others have used it to help stop cell damage. It may also help to improve appetite and increase energy levels. Some people use it to improve mood.. Carnitine, derived from an amino acid, is the generic term for several compounds, including L-carnitine, acetyl-L-carnitine, and propionyl-L-carnitine [ 1 ]. Carnitine is naturally present in many foods—especially foods of animal origin—and is available as a dietary supplement. Carnitine is also synthesized endogenously in the liver.

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Acetyl L-carnitine, also commonly called ALCAR, goes a step further. While acetyl L-carnitine may also help turn fat into energy, it's also able to cross the blood-brain barrier to support brain energy and function. The blood-brain barrier is a protective mechanism that blocks pathogens or toxins from passing through the endothelial membrane.. The standard dose for L-carnitine is between 500-2000 milligrams per day (mg/day). Supplementation with up to 2000 mg/day of L-carnitine is considered safe for humans. [1] There are various other forms of carnitine supplementation available: The equivalent dosage is up to about 2700 mg/day for acetyl-L-carnitine and up to about 2900 mg/day.